A primary theme of the 2009 Molecular Summit on the integration of imaging and diagnostics (Philadelphia, Pennsylvania) was the integration of molecular imaging, diagnostics, and healthcare informatics. Successful convergence of these key components has the potential to transform medicine, leading to faster and more accurate diagnoses and individualized treatments for patients. Thomas Miller, Chief Executive Officer (CEO) for the Workflow & Solutions Division of Siemens Healthcare, discussed the potential to achieve personalized medicine through the integration of technologies.
“As companies like Siemens integrate diagnostic and imaging systems with healthcare information technology, we move closer to a transformation in healthcare – achieving the true potential of personalized medicine,” said Miller. One such concept in advancing personalized medicine is companion therapeutics, in which, based on highly specific diagnosis, a treatment would be also highly specific, targeting the unique characteristics of a disease as it manifests individually, thus improving outcomes.
“What we will see,” explained Miller, “is that a group of patients will be selected from an entire population, and that subgroup of patients will be given a therapy that is specific to their molecular composition and to that of the disease. Our job, as an industry, must focus on characterizing a disease with great precision in order to develop companion therapeutics that we a priori know the effectiveness of a drug.” Administering the most effective drug to the right patient can also reduce costs. “One of the most expensive things you can do in healthcare is to treat a patient with a therapy that is ineffective,” said Miller. “If we can eliminate that possibility, then we can reduce healthcare costs and increase quality.”
Personalized medicine can also lead to decreases in the overall costs of care. One of the key factors in reducing healthcare costs is streamlining workflow, noted Miller. “At Siemens, we look at everything as a workflow challenge,” he said. “Healthcare workflow is nonlinear and has unlimited complexity.” Discovering a hospital that offers the best standard of care in a particular disease and studying this in great detail – analyzing the approach and the workflow with the goal to replicate – and even further innovate – workflow improves quality and efficiency and reduces costs.