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PFA-100® System
The PFA-100 System measures the complex process of primary hemostasis and aids in the rapid detection of platelet dysfunction. It is the first commercially available in vitro testing system to incorporate high-shear flow to provide a realistic hemodynamic environment in the measurement of primary hemostasis.
Helps detect inherited, acquired and drug-induced platelet dysfunction
- Screening test for patients with impaired primary hemostasis, such as von Willebrand disease1
- Verifies efficacy of desmopressin acetate (DDAVP) therapy in pre-surgical patients2
- Assesses the platelet dysfunction due to the effect of Aspirin
- Evaluates platelet dysfunction in children over 1 year of age3
- Evaluates platelet dysfunction in multiple clinical settings, such as presurgical screening, high-risk pregnancy and menorrhagia
The PFA-100 System provides automated assessment for inherited, acquired, or drug-induced platelet dysfunction. It quickly and easily measures platelet plug formation in a small whole blood sample (800 μL) and reports a ”closure time” in 5–8 minutes.
1 Koscielny J, Ziemer S, Radtke H, et al. A practical concept for preoperative identification of patients with impaired primary hemostasis. Clin Appl Thromb Hemost. 2004;10:195-204.
2 Koscielny J, von Tempelhoff GF, Ziemer S, et al. A practical concept for preoperative management of patients with impaired primary hemostasis. Clin Appl Thromb Hemost. 2004;10:155-66.
3 Lippi G, Manzato F, Franchini M, et al. Establishment of reference values for the PFA-100 platelet function analyzer in pediatrics. Clin Exp Med. 2001;1:69-70.
