The PFA-100 System has become the new standard for detection of platelet dysfunction. The PFA-100 Analyzer quickly and easily measures platelet plug formation in a small, whole blood sample (<1 mL) and reports a ”Closure Time” in 5-8 minutes. It is a unique system that challenges platelets under high shear flow conditions similar to the physiologic environment in which platelets normally function. It detects inherited-, acquired- or induced- platelet dysfunction by uniquely simulating, in vitro, the function of platelets in Primary Hemostasis.